Table 5. Nine patients with additional respiratory viruses detected only in their saliva for the second cohort of patients.
| Case Number | Sex/age in years | Underlying medical conditions | Presenting symptom; final diagnosis | Respiratory virus detected in NPAa | Additional virus detected in salivaa | Potential changes in antiviral treatment or infection control practice |
|---|---|---|---|---|---|---|
| 1 | M/56 | Nasopharyngeal carcinoma | Productive cough, dyspnea; pneumonia | Negativeb | Influenza A H1 | Neuraminidase inhibitor |
| 2 | F/78 | Gout | Fever, dyspnea; lower respiratory tract infection | Negativeb | Influenza A H3 | Neuraminidase inhibitor |
| 3 | M/81 | DM, Ca prostate | Productive cough; upper respiratory tract infection | Negativec | Influenza A H3 | Neuraminidase inhibitor |
| 4 | F/81 | Hypertension, hyperlipidemia, IFG | Rhinorrhea, cough, dyspnea, wheeze; pneumonia | EV/RVb | hMPV | Contact precaution |
| 5 | M/72 | DM, hypertension | Fever, rhinorrhea, dry cough; pneumonia | Negativeb | hMPV | Contact precaution |
| 6 | M/55 | Schizophrenia, gout, CVA | Fever, productive cough; pneumonia | Negativec | hMPV | Contact precaution |
| 7 | M/63 | Asthma, Churg-Strauss syndrome | Productive cough, dyspnea; asthmatic attack | Negativeb | EV/RV | Nil |
| 8 | F/63 | Stage IV lymphoma, hypertension, asthma | Fever, productive cough, chills; upper respiratory tract infection | Negativeb | EV/RV | Nil |
| 9 | M/79 | Ischemic heart disease, diabetic nephropathy, Ca prostate with bone metastasis, pemphigoid, bronchiectasis | Fever and dizziness; CAPD peritonitis | Negativec | Coronavirus OC43 | Nil |
Abbreviations: carcinoma, Ca; continuous ambulatory peritoneal dialysis, CAPD; cerebrovascular accident, CVA; diabetes mellitus, DM; enterovirus/rhinovirus, EV/RV; human metapneumovirus, hMPV; impaired fasting glucose, IFG.
Respiratory virus detection was performed using NxTAG Respiratory Pathogen Panel.
Sufficient nasopharyngeal columnar epithelial cells detected during DFA.
Insufficient nasopharyngeal columnar epithelial cells detected during DFA.