Table 2. HBV polymorphisms analyzed by MALDI-TOF MS.

HBV region	Amino acid substitutions	Nucleotide changes
pol	rtT70S	A/T@337
	rtN71T	A/C@341
	rtS78T	T/A@361
	rtL80I(V)	C/T/A/G@367
	rtL82M	C/A@373
	rtV84M	G/A@379
	rtS85A	T/G@382
	rtA86P	G/C@385 A/C@400
	rtP92L	C/T@404
	rtT128N	C/A@512
	rtH133L	A/T@527
	rtS/T135C	A/T@532 C/G@533
	rtI/V163V	A/G@616
	rtF166L	T/C@ 625
	rtI169T	T/C@635
	rtV173L	G/C/T@646
	rtP177L	C/T@659
	rtL179P	T/C@665
	rtL180M	C/T/A@667
	rtA181T(V/S)	G/A/T@670 C/T@671
	rtT184G	A/G@679 C/G@680
	rtV191I	G/A@700
	rtA194T	G/A@709
	rtA200V	C/T@728
	rtS202I	G/T@734
	rtM204V/I	A/G@739 G/C/T@741
	rtM204S	T/G@740 G/T@741
	rtV207I	G/A@748 G/A/T/C@750
	rtS213T	T/A@766
	rtV214A	T/C@770
	rtQ215S	C/T@772
	rtS219T	T/A@784
	rtF221Y	T/A@791
	rtS223A	T/G@796
	rtI224V	A/G@799
	rtL229V/M	T/G/A@814
	rtI233V	A/G@826
	rtH234Q	T/A/G@831
	rtL235I	T/C/A@832
	rtN236T	A/C@836
	rtP237H	C/A@839
	rtN/S/H/A238S	A/C/G@841 T/C@843
	rtY245S	A/C@863
	rtN/H248H	A/C@871
	rtM250V	A/G@877
	rtV/I253I	G/A@886 A/G@895
Basal core promoter/pre-core		A1899G
		G1896A
		C1858T
		A1762T
		G1764A