Table 3.
Outcomes and other measures of the medication management and education intervention
| Categories/variables | Measure | Collection week |
|---|---|---|
| Medication discrepancies | ||
| Between drug name and dosage Frequency of per-patient discrepancies Severity of discrepancies |
Patient interview Questionnaire Medical record review |
t 0, t 3 |
| Medication-related problems (intervention arm only) | ||
| Adverse drug reaction Drug interaction Untreated, undertreated, or overtreated indication Other medication-related barriers |
Patient interview Questionnaire |
t 0, t 3 |
| Adherence | ||
| Self-reported medication adherence Affordability |
MMAS-8 Patient interview |
t 0, t 3 |
| Quality of life | ||
| Health-related quality of life Abdominal and systemic symptoms Emotional functioning, fatigue, and worry Daily activity |
CLDQ Brief IPQ |
t 0, t 3 |
| Beliefs and perceptions | ||
| General medication beliefs Beliefs about liver disease medications Illness perceptions |
BMQ-General BMQ-Specific Brief IPQ |
t 0, t 3 |
| Knowledge/health literacy | ||
| Knowledge of causation Dietary modification including sodium restriction Self-monitoring requirements Safe analgesia Source of medication-related information |
Questionnaire Brief IPQ |
t 0, t 3 |
| Hospitalization | ||
| Liver-related hospitalization Non-liver-related hospitalization Duration of stay |
Medical record review |
t
3,
t
4
(and 3 years) |
| Survival | ||
| Liver-related mortality Non-liver-related mortality |
Medical record review |
t
3,
t
4
(and 3 years) |
| Cost | ||
| Cost of service implementation Potential cost savings |
Cost modeling | After study completion |
Abbreviations: BMQ Beliefs about Medicines Questionnaire, Brief IPQ Brief Illness Perception Questionnaire, CLDQ Chronic Liver Disease Questionnaire, MMAS-8 Eight-question Morisky Medication Adherence Scale