Table 1.
IC50 values of Cladosporol A against NC1 60 panel of human cancer cell lines of different tissue origin. Data are expressed as the mean ± SD of three similar experiments
| IC50(μM) | |||||
|---|---|---|---|---|---|
| S.No | MCF-7 (Breast cancer) | A549 (Lung cancer) | HCT-116 (Colon cancer) | PC-3 (Prostate cancer) | OVCAR-3 (Ovarian Cancer) |
| Cladosporol A | 8.7 ± 0.205 | 11.7 ± 0.505 | 12 ± 0.505 | 15.6 ± 0.360 | 10.3 ± 0.556 |
| Paclitaxel | 0.0.25 ± 0.001 | 0.75 ± 0.05 | 8.5 ± 0.620 | 0.48 ± 0.003 | 2.6 ± 0.120 |
| Doxorubicin | 0.1 ± 0.006 | 0.087 ± 0.009 | 0.096 ± 0.005 | 0.05 ± 0.006 | 0.13 ± 0.008 |