Table 1. Patients characteristics, complete remission rates, disease-free survival and overall survival.
| N (%) | CR % | Median DFS months | P | 2 years DFS % | median OS months | P | 2 years OS % | |
|---|---|---|---|---|---|---|---|---|
| All patients | 117 | 56 | 7.9 | 12.3 | 10.0 | 21.4 | ||
| Age ⩾70 | 48 (41) | 58.3 | 8.6 | 0.12 | 17.9 | 9.3 | 0.67 | 20.8 |
| PS 0 vs 1 vs 2 | 36 vs 66 vs 12 | 72 vs 48 vs 50 | 15.7 vs 5.1 vs 6.3 | 0.012 | 19.2 vs 6.3 vs 0 | 18.7 vs 9.2 vs 4.6 | 0.002 | 41.7 vs 13.6 vs 8.3 |
| WBC >2.9 × 109/l | 58 (49.5) | 50 | 7 | 0.16 | 10.3 | 8.6 | 0.017 | 13.8 |
| Poor cytogenetics | 83 (70.9) | 53 | 5.1 | 0.004 | 6.8 | 8.1 | 0.0001 | 10.8 |
| MDS only | 19 (16.2) | 68.4 | 16.8 | 0.008 | 30.8 | 37.2 | 0.0001 | 52 |
| Therapy-related AML only | 10 (8.5) | 80 | 12.4 | 0.58 | 12.5 | 17.2 | 0.11 | 50 |
Abbreviations: AML, acute myeloid leukemia; CR, complete remission; DFS, disease-free survival; MDS, myelodysplastic syndrome; OS, overall survival; PS, performance status.