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Effects of MCP-1 on MMP-2/9 expression and MMP-2 activity in MCF-7 cells. The cells were incubated with or without the indicated inhibitors (RS, U1026 and LiCl) for 1 h before MCP-1 treatment. The expression and activity levels of MMP-2/9 were determined by real-time PCR (a) and gelatin zymography (b), respectively.
