TABLE 2.
Virulence of the ΔyopK mutant in BALB/c mice determined via i.v. and s.c. challenges
| Y. pestis strain | LD50 (CFU) after challenge: |
||
|---|---|---|---|
| i.v. |
s.c. | ||
| First | Second | ||
| 201 | 94 | 31 | 6 |
| 201 ΔyopK | 1,778 | 1,380 | 10 |
| 201 ΔyopK-CyopK | 73 | 89 | 8.9 |
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