Table 3. WHV–woodchuck genome junctions identified in liver biopsies after de novo infection.
| Animal/ liver biopsy number | Total of virus–host junctions detected (no) | WHV sequence (nt. position) | Host sequence (bp length) | Chromosome numbera | Sequence locusa | Host sequence (nt. position) | Genea | Total of virus–virus junctions detected (no) |
|---|---|---|---|---|---|---|---|---|
| Cw1/M LBx2-1 h.p.i. | 3 | PS3200–3256 | 33 | 11 | q21 | 95720503–95720470 | MAML2 | 3 |
| X1853–1876 | 16 | UI | UI | UI | UI | |||
| PS2785–2934 | 36 | 15 | q25 | 84783482–84783518 | EFTUD1P1 | |||
| Cw2/F LBx2-1 h.p.i. | 5 | X1913–1853 | 48 | 2 | p14 | 69870009–69870057 | AAK1 | 12 |
| X1913–1853 | 118 | 2 | p14 | 69784039–69784157 | AAK1 | |||
| X1913–1853 | 19 | 6 | q14.1 | 83777393–8377412 | KIAA1117 | |||
| X1910–1853 | 20 | 20 | q12 | 39989149–39989169 | LPIN3 | |||
| PS3030–3009 | 17 | 20 | q13.2 | 178193731–178193748 | PHACTR3 | |||
| Cw4/M LBx2–3 h.p.i. | 3 | PS3250–3308 | 75 | UI | UI | UI | UI | 4 |
| PS3251–3308 | 68 | UI | UI | UI | UI | |||
| PS3251–3308 | 70 | UI | UI | UI | UI | |||
| Cw1/M LBx3–6 w.p.i. | 2 | X1855–1876 | 16 | UI | UI | UI | UI | 0 |
| X1854–1877 | 18 | 16b | q13b | 2650–2632 | NLRC5b | 0 | ||
| Cw2/F LBx3–6 w.p.i. | 2 | X1623–1501 | 210 | UI | UI | UI | UI | 0 |
| X1548–1501 | 137 | UI | UI | UI | UI | |||
| Cw3/F Bx3–6 w.p.i. | 1 | X1772–1821 | 81 | UI | UI | UI | UI | 2 |
| Cw4/M LBx3–6 w.p.i. | 2 | PS3250–3308 | 68 | UI | UI | UI | UI | 4 |
| X1651–1810 | 26 | X | p21.1 | 18674290–18674316 | HDAC-9 |
Abbreviations: AAK1, AP-1 associated kinase; EFTUD1P1, elongation factor Tu GTP binding domain containing 1 pseudogene; HDAC-9, histone deacetylase-9; Kazusa cDNA 1117; KIAA1117; LPIN3, lipin-3; MAML2, mastermind-like 2; NLRC5, NLR family CARD domain containing 5; PHACTR3, phosphatase and actin regulator 3; UI, unidentified sequence.
a
Based on homology with human genome.
b
Based on homology with mouse genome.