Table 1. Lung tumor incidence and phenotypes.
Rb1 ablated |
|||
---|---|---|---|
p16+/+ | p16+/− | p16−/− | |
Total animals | 37 | 36 | 26 |
Animals with lung tumors (%) | 6 (16) | 10 (28) | 8 (31) |
Multifocal tumors (%) | 3 (8) | 5 (14) | 4 (15) |
Total tumors | 9 | 21 | 17 |
SCL tumors (%) | 0 (0) | 2 (10) | 4 (24) |
NSCL tumors (%) | 9 (100) | 19 (90) | 13 (76) |
Metastatic tumors (%) | 0 (0) | 3 (14) | 1 (6) |
Abbreviations: NSCL, non-small cell lung; SCL, small cell lung.