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Brain water content of AdHIF-α group decreased significantly versus CIR and Ad groups at 24 h and 72 h postreperfusion (P < 0.05). *P < 0.05, AdHIF-1α group versus CIR and Ad groups at 24 h and 72 h postreperfusion. The data are expressed as mean ± standard deviation (n = 6). HIF-1α: Hypoxia-inducible factor-1α; Ad: Recombinant adenovirus; AdHIF-1α: Recombinant adenovirus vector containing HIF-1α; CIR: Cerebral ischemia and reperfusion.
