. 2017 Jul 20;130(14):1707–1714. doi: 10.4103/0366-6999.209891

Table 1.

Basic data of enrolled studies comparing lung protection in patients who underwent thoracic surgery with Dex or a placebo

Study ID	Patients’ age (years)		Number of patients		Management of Dex	Jadad

	Dex	Placebo	Dex	Placebo
Xia R et al. 2013	53 ± 14	55 ± 15	23	22	Dex: 1.0 µg·kg⁻¹·h⁻¹ 10 min after induction, later 0.7 µg·kg⁻¹·h⁻¹	4
Lee SH et al. 2016	68.4 ± 6.4	69.4 ± 8.7	25	25	Dex: 1.0 µg·kg⁻¹·h⁻¹ 10 min after the patient was hemodynamically stable 30 min after the initiation of OLV, later 0.5 µg·kg⁻¹·h⁻¹	5
Xia R et al. 2015	55 ± 12	56 ± 11	25	24	Dex: 1.0 µg·kg⁻¹·h⁻¹ 10 min after induction, later 0.7 µg·kg⁻¹·h⁻¹	4
Kernan S et al. 2011	53.8 ± 13.5	51.2 ± 17.8	9	10	Dex: 0.3 µg/kg 10 min after 10 min of OLV, later 0.3 µg·kg⁻¹·h⁻¹	5
Guo QM et al. 2016	62 ± 13	60 ± 12	20	20	Dex: 1.0 µg·kg⁻¹·h⁻¹ 10 min before induction, later 0.5 µg·kg⁻¹·h⁻¹	3
Lai Y et al. 2013	48.3 ± 12.5	46.2 ± 15.6	11	11	Dex: 0.3 µg/kg 10 min, later 0.3 µg·kg⁻¹·h⁻¹	3
Liu YT et al. 2016	59 ± 5	60 ± 6	36	36	Dex: 0.5 µg/kg 15 min before induction, later 0.3 µg·kg⁻¹·h⁻¹	5
Tao GH et al. 2016	62.7 ± 6.4	62.7 ± 6.3	20	20	Dex: 1.0 µg·kg⁻¹·h⁻¹ 20 min before induction, later 0.5 µg·kg⁻¹·h⁻¹	3
Xue F et al. 2015	59.6 ± 5.6	60.2 ± 6.2	30	30	Dex: 0.6 µg/kg 10 min before induction, later 0.5 µg·kg⁻¹·h⁻¹ at the beginning of surgery	3
Yu HB et al. 2014	57 ± 9	58 ± 7	19	19	Dex: 1.0 µg·kg⁻¹· h⁻¹ 15 min before induction, later 0.5 µg·kg⁻¹·h⁻¹	3
Zhang LL et al. 2014	57.3 ± 8.7	56.8 ± 7.9	20	20	Dex: 0.6 µg/kg 10 min before induction, later 0.4 µg·kg⁻¹·h⁻¹	4
Zhang QY et al. 2015	57 ± 14	55 ± 12	20	20	Dex: 1.0 µg·kg⁻¹·h⁻¹ over 10 min before operation, later 0.5 µg·kg⁻¹·h⁻¹	3
Zhao HB 2016	54.1 ± 5.3	53.4 ± 4.6	25	25	Dex: 1.0 µg·kg⁻¹·h⁻¹ 10 min after induction, later 0.5 µg·kg⁻¹·h⁻¹	3
Zhu XB et al. 2015	40 ± 5	42 ± 7	30	30	Dex: 1.0 µg·kg⁻¹·h⁻¹ 10 min before induction, later 0.4 µg·kg⁻¹·h⁻¹	3

Dex: Dexmedetomidine; OLV: One-lung ventilation.