Figure 1.

Mean ± SD percentage change in body weight of gray foxes (Urocyon cinereoargenteus) administered RABV vaccine on the basis of group (A) and on the basis of sex (B). Body weight was obtained at the time of arrival at our facility (day −90), at a health examination performed after a 14-day acclimation period (day −76), before endoscopic delivery of vaccine (day 0), and at the time of blood collection on days 7, 14, 21, and 28. Mean and SD were calculated for each group by the percentage change for each fox calculated by use of the body weight obtained on day −76 as the denominator. In panel A, results are reported for all 8 foxes (black circles), 3 foxes (2 males and 1 female) that received 1 mL of nonencapsulated RABV PBV (mean ± SD; 5.2 ± 0.09 log₁₀ ffu/mL; group 1 [black squares]), 3 foxes (3 females) that received 1 mL of alginate-encapsulated RABV PBV (4.3 ± 0.2 log₁₀ ffu/mL; group 2 [black triangles]), and 2 foxes (2 males) that received 1 mL of RABV ERAG333 (8.0 ± 0.2 log₁₀ ffu/mL; group 3 [inverted black triangles]). In panel B, results are reported for all 8 foxes (black circles), the 4 female foxes (white circles), and the 4 male foxes (white squares).