Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 May 25;8(5):e2821. doi: 10.1038/cddis.2016.216

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 The Author(s)

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Knocking down of RGS2 expression by shRNA in β cells increases cell apoptosis. (a) Percentage of apoptotic cells in RGS2-knockdown (RGS2 shRNA) and control (control shRNA) cells cultured under normoxia (20% O₂) and hypoxic (1% O₂) conditions for 24 or 48 h (flow-cytometric analysis). (b) Protein expression of cleaved Caspase-3 and β-actin analyzed in βTC3 cells transfected with RGS2 shRNA or control shRNA (western blot analysis) at 8 h after hypoxia treatment. Data are representative from at least three individual experiments. *P<0.05, ANOVA test