Figure 2.

MiR-18a-5p can promote cell proliferation and migration of NSCLC cell lines. (a, b) H23, H1299 and A549 cells were transfected with NC or miR-18a-5p mimic/NC or miR-18a-5p inhibitor, and cell proliferation was determined by CCK-8. (c, d) The apoptosis distributions of H23, H1299 and A549 cells were transfected with NC or miR-18a-5p mimic/NC or miR-18a-5p inhibitor for 48 h then detected by flow cytometry. (e, f) 48 h after transfected with NC or miR-18a-5p mimic/NC or miR-18a-5p inhibitor, the results of wound healing assays and Transwell assays in H23, H1299 and A549 cells. n=3–4 independent experiments, Error bars represent the mean±S.E.M. *P<0.05, **P<0.01, ***P<0.001