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. 2017 May 25;8(5):e2831. doi: 10.1038/cddis.2017.149

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Copyright © 2017 The Author(s)

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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TRIM45 promotes apoptosis in GBM cells. (a and b) The TRIM45-overexpressing (a) and KO (b) U87 and LN229 cells were incubated with FITC-Annexin V solution and subjected to FACS analysis. (c and d) Lysates of TRIM45-overexpressing (c) and TRIM45 KO (d) U87 and LN229 cells were immunoblotted with an anti-caspase-3 antibody. β-Actin was used as a loading control. Each bar represents the mean±S.D. of three independent experiments. **P<0.01