Figure 5.

Immunohistochemistry detects increased angiogenesis in the rat brain with CA-GCII by transplanted BMMSCs. (a) Microscopic images from temporal cortex area in coronal sections stained with anti-RECA-1 antibody. Arrows indicate RECA-1-positive microvessels. (b) Quantification of microvessels is expressed as microvessel density (number of stained vessels per microscopic field). Data are depicted as mean±S.D. ** indicates P-value <0.001 for Student’s t-test. Sham, normal control; Blank, CA-GCII with PBS; BM-Vehicle, CA-GCII with naïve BMMSCs; BM-B&V, CA-GCII with BMMSCs co-transduced with BDNF- and VEGF-lentiviruses