Table 1. Correlation between the clinicopathologic characteristics and miR-23b expression in HCC tissues.
| Factor | Total number |
n |
P-value | |
|---|---|---|---|---|
| MiR-23b high expression | MiR-23b low expression | |||
| Gender | ||||
| Male | 60 | 39 | 21 | |
| Female | 10 | 5 | 5 | 0.285 |
| Age (years) | ||||
| ⩽60 | 51 | 34 | 17 | |
| >60 | 19 | 10 | 9 | 0.210 |
| Tumor size (cm) | ||||
| ⩽5 | 48 | 26 | 22 | |
| >5 | 22 | 18 | 4 | 0.023 |
| Tumor number | ||||
| 1 | 53 | 30 | 23 | |
| ⩾2 | 17 | 14 | 3 | 0.049 |
| AFP (ng/ml) | ||||
| ⩽20 | 30 | 20 | 10 | |
| >20 | 40 | 20 | 20 | 0.375 |
| ALT (U/l) | ||||
| ⩽40 | 52 | 33 | 19 | |
| >40 | 18 | 11 | 7 | 0.537 |
| BCLC stage | ||||
| 0–A | 53 | 29 | 24 | |
| B–C | 17 | 15 | 2 | 0.011 |
| Liver capsule invasion | ||||
| No | 66 | 41 | 25 | |
| Yes | 4 | 3 | 1 | 0.524 |
| Liver cirrhosis | ||||
| Absent | 3 | 2 | 1 | |
| Present | 67 | 42 | 25 | 0.691 |
| Hepatitis B status | ||||
| Negative | 5 | 3 | 2 | |
| Positive | 65 | 41 | 24 | 0.619 |
Abbreviations: AFP, α-fetoprotein; ANLT, adjacent non-tumor liver tissue; BCLC, Barcelona Clinic Liver Cancer; HCC, hepatocellular carcinoma
MiR-23b high expression: expression of miR-23b in HCC tissues was higher than that in corresponding ANLTs; miR-23b low expression: expression of miR-23b in HCC tissues was lower than that in corresponding ANLTs. Bold numbers indicate significant differences (P<0.05)