Table 2. Linear Mixed Effects Models Testing Associations Between SSRT and Subjective Response to Amphetamine (Aim 1).
Estimate | SE | t | p | |
---|---|---|---|---|
ARCI MBG (Euphoria) | ||||
Order | 0.44 | 0.46 | 0.95 | 0.346 |
Sex | −0.19 | 0.48 | 0.41 | 0.685 |
Age | 0.01 | 0.07 | 0.13 | 0.898 |
SSRT | −0.01 | 0.02 | 0.56 | 0.578 |
Drug | −0.16 | 0.40 | 0.39 | 0.696 |
Time (linear) | −0.33 | 0.17 | 1.90 | 0.061 |
Time2 (quadratic) | 0.04 | 0.02 | 1.92 | 0.057 |
SSRT × Drug | < −0.01 | 0.02 | 0.16 | 0.875 |
SSRT × Time | < −0.01 | 0.01 | 0.48 | 0.631 |
SSRT × Time2 | < 0.01 | < 0.01 | 0.38 | 0.707 |
Drug × Time | 2.00 | 0.15 | 13.41 | < 0.001 |
Drug × Time2 | −0.21 | 0.02 | 10.38 | < 0.001 |
SSRT × Drug × Time | 0.02 | 0.01 | 3.49 | < 0.001 |
SSRT × Drug × Time2 | < −0.01 | < 0.01 | 2.68 | 0.007 |
ARCI A (stimulation) | ||||
Order | 0.46 | 0.32 | 1.44 | 0.155 |
Sex | −0.41 | 0.33 | 1.24 | 0.220 |
Age | −0.01 | 0.05 | −0.25 | 0.803 |
SSRT | < −0.01 | 0.01 | 0.02 | 0.983 |
Drug | −0.13 | 0.26 | 0.50 | 0.619 |
Time (linear) | −0.16 | 0.07 | 2.28 | 0.023 |
Time2(quadratic) | 0.02 | 0.01 | 2.04 | 0.041 |
SSRT × Drug | < 0.01 | 0.01 | 0.21 | 0.837 |
SSRT × Time | < −0.01 | < 0.01 | 0.52 | 0.601 |
SSRT × Time2 | < 0.01 | < 0.01 | 0.01 | 0.989 |
Drug × Time | 1.30 | 0.10 | 13.37 | < 0.001 |
Drug × Time2 | −0.14 | 0.01 | 10.14 | < 0.001 |
SSRT × Drug × Time | 0.01 | < 0.01 | 2.88 | 0.004 |
SSRT × Drug × Time2 | < −0.01 | < 0.01 | 2.28 | 0.023 |
Abbreviation: SSRT, stop signal reaction time.
Note. Significant effects are indicated in a bold font.