Table 1.
List of Clinical Trials With Combination of DC Vaccines and Check Point Inhibitors
| Check point inhibitors | Cancer type | Type of DC vaccine | ClinicalTrials.gov Identifier: |
|---|---|---|---|
| PD-1 | Acute myelogenous leukemia | DC/AML fusion | NCT01096602 |
| PD1 (CT-011) | Myeloma | DC/myeloma fusion | NCT01067287 |
| PD-1 (CT011) | Renal cell carcinoma | DC/Renal cell carcinoma fusion | NCT01441765 |
| PD-1 (Nivolumab) | Brain tumor | CMV pp65-LAMP mRNA pulsed autologous DCs | NCT02529072 |
| CTLA-4 (ipilimumab) | Melanoma | TriMix-DC (MAGE-A3, MAGE-C2, tyrosinase, and gp100) | NCT01302496 |
| CTLA-4 (CP-675,206) | Melanoma | MART-1 peptide pulsed DC | NCT00090896 |