Table 2.

Demographic information of enrolled subjects

Group	Healthy control	MCI due to AD	Early-stage AD
Numbers	68	24	31
Age (years)	62.7 ± 9.7	71.0 ± 10.3	72.1 ± 10.7
CDR	0	0.5	0.5–1
MMSE	28.6 ± 1.1	24.6 ± 2.2*	22.2 ± 2.9*,†
ϕ Aβ 1–42 (pg/mL)	15.82 ± 0.73	17.52 ± 1.22	18.61 ± 1.55
ϕ Tau (pg/mL)	13.38 ± 6.85	33.33 ± 7.77	53.57 ± 22.87

CDR clinical dementia ranking, MMSE Mini-Mental State Examination

^†Significant group difference between MCI due to AD and early-stage AD groups at a significance level of p < 0.01

* Significant difference between the healthy control and MCI due to AD or early-stage AD groups by ANOVA at a significance level of p < 0.01