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. 2017 Jun 1;8(6):e2846. doi: 10.1038/cddis.2017.231

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Copyright © 2017 The Author(s)

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Deletion of furin in primordial follicle oocytes causes early secondary follicle developmental arrest. (a) FURIN immunohistochemistry showing specific FURIN protein depletion in the oocytes of fur^fl/fl and fur^fl/fl; Gdf9-Cre mice. Scale bar=50 μm (b) Histology of ovarian sections from fur^fl/fl and fur^fl/fl;Gdf9-Cre 6-week-old females stained with H&E. Scale bars=50 μm