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. 2017 Jun 22;8(6):e2895. doi: 10.1038/cddis.2017.244

Table 2. MYBL2 deregulation associated with patient outcome in different cancer entities.

Tumor entity MYBL2 deregulation Association with patient survival References
Acute myeloid leukemia Overexpression MYBL2 expression is an independent prognostic factor for disease-free survival and cumulative incidence of relapse Fuster et al.17
Bladder carcinoma Overexpression (amplification) Overrepresentation of amplicons in high-grade and recurrent cases Nord et al.87
Breast cancer Overexpression Overexpression is associated with short overall patient survival and short disease-free survival Inoue and Fry88
Colorectal cancer Overexpression Overexpression is correlated with worse disease-free survival and MYBL2 is an independent prognostic factor for poor patient survival Ren et al.89
Esophageal squamous cell carcinoma Overexpression (amplification) High MYBL2 expression and high MYBL2 copy-number are associated with poor patient survival Qin et al.90
Hepatocellular carcinoma Overexpression, high phosphorylation levels High levels of total and phosphorylated MYBL2 and high levels of LIN9–MYBL2 complex in HCC with poorer outcome Calvisi et al.91
Neuroblastoma Overexpression MYBL2 expression is associated with increased risk of death and worse overall survival Raschellà et al.92
Renal cell carcinoma Positivity Positivity for MYBL2 expression is significantly correlated with clinical stage III and IV Sakai et al.93