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. 2017 Jun 8;8(6):e2866. doi: 10.1038/cddis.2017.257

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Copyright © 2017 The Author(s)

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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ARRDC4 expression is positively correlated with serum proinflammatory cytokines concentration in EV71-infected HFMD patients and healthy controls. (a) Q-PCR analysis of ARRDC4 mRNA expression in PBMCs from EV71-infected HFMD patients (n=30) and controls (n=30), which normalized by the mean expression value. Data are shown as mean±S.D., **P<0.01. (b) The correlation between ARRDC4 mRNA expression level (assayed by Q-PCR) and IL-6, TNF-α, CCL3 serum concentration (assayed by ELISA) in patients were evaluated with the Pearson correlation test