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(a) Electrophoresis of cDNA amplicons of IVS7 transcripts. Primer oligonucleotides flanking exon 2 and 9 were used to amplify cDNA from SB1690CB (right lane)12 and MMC-resistant pedigree SBRes (middle lane). Additional band (Del E5+7), indicating an additional dominant transcript in SBRes, and a dominant smaller transcript in SB1690CB, Del 4–7. (b) cDNA sequence of BRCA2Δ5+7 showing exon/exon boundaries between exon 4 and 6, and 6 and 8
