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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Expert Opin Drug Discov. 2016 Nov 7;12(1):89–103. doi: 10.1080/17460441.2017.1253676

Figure 1. Schematic illustration of BBB anatomy.

Figure 1

A cross-section of brain microcapillary representing luminal compartment composed of basal lamina, endothelial cells and pericytes tightly ensheathed by the astrocytic end-feet. Tight junctions (TJs), present between the cerebral endothelial cells selectively excludes paracellular trafficking of substances from entering into brain.