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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Expert Opin Drug Discov. 2016 Nov 7;12(1):89–103. doi: 10.1080/17460441.2017.1253676

Figure 2. Schematic diagram of currently available in vitro BBB models simulating in vivo NVU milieu based on two distinct principles- static vs dynamic culture.

Figure 2

Static models include transwell and 3D ECM platform while dynamic models utilize hollow fiber based apparatus or micro fluidic devices.