Table 4.
Inter and Intra Assay Variation between Abbott Real Time HIV-1 and GeneXpert HIV-1 Quant
| NHP spiked with high VL plasma | NHP spiked with viral stock | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| HIV-1 viral load (copies/ml) | Coefficient of variation (% CV) | HIV-1 viral load (copies/ml) | Coefficient of variation (% CV) | ||||||
| Inter-Assay | Intra-Assay | Inter-Assay | Intra-Assay | ||||||
| Abbott | GeneXpert | Abbott | GeneXpert | Abbott | GeneXpert | Abbott | GeneXpert | ||
| 200 | 4.11 | 1.97 | 4.77 | 3.34 | 40 | 1.53 | 6.96 | 4.28 | 2.33 |
| 2000 | 1.08 | 1.45 | 1.42 | 0.31 | 4000 | 1.03 | 3.17 | 0.77 | 10.66 |
| 20,000 | 0.86 | 2.74 | 2.51 | 0.97 | 40,000 | 0.28 | 6.84 | 0.42 | 0.96 |
| 2,00,000 | 0.57 | 0.36 | 1.74 | 1.11 | 4,00,000 | 0.60 | 3.00 | 0.49 | 2.89 |
| 20,00,000 | 0.81 | 0.58 | 0.78 | 0.45 | 40,00,000 | 0.69 | 0.78 | 0.33 | 0.78 |