Table 7.
Odds ratios (ORs) and corresponding 95% confidence intervals (CI) for the associations between body size at age 18 years and tumor size in KARMA
| Body size at age 18 | T0–T1 (n) | T2–T4 (n) | Multivariable OR (95% CI)a |
|---|---|---|---|
| Subset of women with percent mammographic density <25% | |||
| Small | 81 | 43 | 1.00 (Reference) |
| Medium | 223 | 61 | 0.53 (0.33–0.85) |
| Large | 33 | 6 | 0.34 (0.13–0.88) |
| P trend | 0.008 | ||
| Subset of women with percent mammographic density ≥25% | |||
| Small | 87 | 49 | 1.00 (Reference) |
| Medium | 143 | 68 | 0.83 (0.51–1.33) |
| Large | 15 | 5 | 0.56 (0.19–1.68) |
| P trend | 0.249 | ||
T tumor size
aAdjusted for age, age at menarche, number of children, use of hormone replacement therapy and family history of breast cancer