Table 3.
HR (95% CI) | P | |
---|---|---|
Diagnosis year/cohort | <0.001 | |
2005 | ||
Women age ≤ 40 | Reference | |
Women age 41–45 | 0.71 (0.60–0.84) | |
2006 | ||
Women age ≤ 40 | 1.70 (1.44–2.00) | |
Women age 41–45 | 0.97 (0.82–1.14) | |
2007 | ||
Women age ≤ 40 | 2.11 (1.81–2.46) | |
Women age 41–45 | 1.39 (1.19–1.62) | |
2008 | ||
Women age ≤ 40 | 2.71 (2.34–3.13) | |
Women age 41–45 | 1.83 (1.59–2.12) | |
2009 | ||
Women age ≤ 40 | 3.42 (2.97–3.94) | |
Women age 41–45 | 2.23 (1.94–2.57) | |
2010 | ||
Women age ≤ 40 | 4.03 (3.50–4.65) | |
Women age 41–45 | 2.75 (2.39–3.17) | |
2011 | ||
Women age ≤ 40 | 4.77 (4.14–5.50) | |
Women age 41–45 | 3.48 (3.03–4.00) | |
2012 | ||
Women age ≤ 40 | 6.05 (5.26–6.97) | |
Women age 41–45 | 4.63 (4.03–5.33) | |
Insurance plan type† | <0.001 | |
PPO | Reference | |
CDHP | 1.14 (1.05–1.24) | |
Comprehensive | 1.01 (0.87–1.17) | |
EPO | 1.05 (0.93–1.19) | |
HDHP | 1.26 (1.13–1.40) | |
HMO | 0.86 (0.82–0.91) | |
POS | 1.03 (0.97–1.10) | |
POS with capitation | 1.17 (0.98–1.41) | |
Missing/unknown | 0.90 (0.83–0.98) | |
Region | <0.001 | |
South | Reference | |
Northeast | 1.15 (1.09–1.21) | |
South Central | 1.18 (1.13–1.23) | |
West | 1.06 (1.00–1.11) | |
Missing/unknown | 1.18 (1.06–1.32) |
The outcome was the first BRCA1/2 testing claim recorded, using a Cox proportional hazards model that included the three independent variables listed in this table.
Insurance plan type: PPO, preferred provider organization; CDHP, consumer-driven health plan (PPO combined with a health reimbursement arrangement); EPO, exclusive provider organization (all care managed by a primary care physician with referrals required, payment non-capitated); HDHP (high deductible health plan combined with health savings account); HMO, health maintenance organization; POS, point-of-service (primary care physician manages care; patients incentivized to use particular providers).