The smooth spline estimates the hazard ratio of cardiovascular events, according to systolic blood pressure (SBP) (mmHg) measured in the dialysis unit among CRIC participants. All analyses are adjusted for age, gender, race/ethnicity, tobacco use, body mass index, diabetes, history of cardiovascular disease, Kt/V, serum albumin and hemoglobin level. Dotted lines represent 95% confidence intervals. Below each spline is the histogram of the distribution of systolic blood pressure to indicate the range of the majority of the data.