Table 2.

Weighted baseline characteristics of the EPOSA study subjects, stratified by AUSCAN for hand OA physical function subscale score and grip strength^*

	AUSCAN for hand OA physical function			Grip strength
	More impaireda (n = 604)	Other (n = 1,638)	P	Lessb (n=680)	Other (n = 1,562)	P
Women	84.64	46.91	<0.0001	58.19	57.23	0.6778
Age, median (IQR), years	74.3 (69.5-79.8)	72.4 (68-77)	<0.0001	76.0 (72-81)	72.0 (68-76)	<0.0001
Country of origin			0.1783			0.4717
Italy	18.00	21.17		18.29	21.11
Netherlands	25.76	23.04		24.47	23.52
Spain	21.86	20.71		21.94	20.65
Sweden	21.95	20.21		19.89	21.04
UK	12.44	14.87		15.41	13.67
Less than secondary education	49.03	42.00	0.0030	47.76	42.39	0.0214
Obesity	29.87	24.23	0.0069	24.46	26.38	0.3505
Cognitive impairment	13.49	8.06	0.0001	13.37	8.02	0.0001
Anxiety	31.25	17.82	<0.0001	24.36	20.44	0.0428
Depression	20.28	9.39	<0.0001	18.20	10.03	<0.0001
Chronic lung disease	16.07	11.53	0.0044	14.88	11.94	0.0608
Cardiovascular disease	27.56	24.59	0.1525	29.95	23.53	0.0017
Peripheral artery disease	11.66	11.22	0.7711	14.25	10.13	0.0057
Diabetes mellitus	11.83	13.19	0.3941	14.72	12.00	0.0838
Stroke	7.28	4.50	0.0094	6.46	4.79	0.1119
Cancer	14.89	12.25	0.0993	12.81	13.07	0.8740
Osteoporosis	29.68	12.71	<0.0001	23.05	15.15	<0.0001
Comorbidity (≥3 diseases)	38.42	20.41	<0.0001	33.91	21.88	<0.0001
Clinical hand osteoarthritis	46.90	5.68	<0.0001	27.01	13.18	<0.0001
AUSCAN for hand OA pain suscale scorec, median (IQR)	20 (0-35)	0 (0-0)	<0.0001	0 (0-20)	0 (0-25)	<0.0001

^*Except were indicated otherwise, values are percent of subjects. EPOSA = European Project on OSteoArthritis; IQR = interquartile range;

^aA score higher than the third quartile on the AUStralian/CANadian Osteoarthritis Hand Index (AUSCAN) for hand osteoarthritis (OA) physical function subscale.

^bA score at the first tertile of subsample distribution stratified by sex and country of origin

^cPossible hand pain scores ranges from 0 to 100 (standardized x 100/20), with 0 indicating no pain.