Fig 4. Numbers of pentamer+ CD8+ T-cells present in tissue compartments.
(A) D7 post boost, n = 3–4 mice per group. (B) D42 post boost, n = 3–4 mice per group. (C) Breadth of antigen-specific CD8+ T-cell response shown as IFN-γ production upon stimulation with peptides representing four different CD8 T-cell epitopes of the HCV-NS3 antigen at D7 post boost. n = 3–4 mice per group Error bars represent standard error of the mean. ns = no significance between the means determined by one-way ANOVA. Asterisks represent significance analyses following post hoc Bonferroni testing between Ad5 and VV or Ad5 and MVA immunized mice. * = p value <0.05; ** = p value<0.01, *** = p value <0.0001.