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. 2017 Mar 29;8(26):42602–42612. doi: 10.18632/oncotarget.16645

Figure 3. Administration of Annexin V promotes tumor necrosis in vivo.

Figure 3

(A) Histological analysis of tumor necrosis comparison among different groups. black arrows, necrotic cells. (B) Annexin V does not induce cell death of B16F10 tumor cells. B16F10 cells were treated with different concentrations of Annexin V and assayed by flow cytometry with staining of Annexin V-FITC and 7-AAD. Early/primary apoptotic cells (Annexin V+/7-AAD−), late/secondary apoptotic cells (Annexin V+/7-AAD+) and necrotic cells (Annexin V−/7-AAD+) were distinguished.