Table 1. Regression analysis for treatment effects on tumor growth.
| Treatment | n | Growth curveav(d) | R2 | Tumor doubling time(d)b | Tumor growth delay time(d)c |
|---|---|---|---|---|---|
| PBS | 8 | ln(V) = 0.3474×d + 3.2983 | 0.98 | 2.5 | 9.4 |
| DTIC 40 mg/kg | 8 | ln(V) = 0.1834×d + 3.4491 | 0.92 | 6.9 | 22.5 |
| AnnexinV 5.0 mg/kg | 8 | ln(V) = 0.3125×d + 3.2922 | 0.98 | 3.8 | 14 |
| AnnexinV 10.0 mg/kg | 8 | ln(V) = 0.287×d + 3.0596 | 0.97 | 5.1 | 16.7 |
aRegression growth curves summarize volume (V, mm3) dependence on time (d, days) from initial treatment, with correlation coefficients indicated by r.
bTumor doubling time was derived from exponential growth curves.
cGrowth delay was determined by assessing the time interval to 1000 mm3 compared with the PBS control.