Table 3. Hazard ratios and 95% confidence intervals for prostate cancer recurrence per 25% increase in the gene expression signature based on Gleason score.

Patients	Model	Recurrence
		HR	95% CI	P-value
All	Signature alone a	1.65	1.36, 1.98	2.4×10−7
	Multivariate b	1.51	1.24, 1.82	2.7×10−5
GS 7	Signature alone a	1.44	1.14, 1.82	0.002
	Multivariate b	1.38	1.09, 1.76	0.008

HR: hazard ratio, CI: confidence interval, GS: Gleason score

^a Signature (per 25% increase)

^b Adjusted for age at diagnosis and pathological stage