Table 2. Comparisons of lymphocyte subsets between NSCLC patients and healthy controls.

Immune parameter	Healthy control	NSCLC-D	NSCLC-R	P
CD3+ T cells	72.87±5.40	69.63±12.83	67.89±11.02	0.398
CD4+ T cells	42.26±4.70	39.85±8.49	33.53±9.74	0.002
CD8+ T cells	27.05±4.21	28.65±9.12	33.20±7.00	0.025
CD4/CD8 ratio	1.77±0.29	1.60±0.63	1.24±0.60	0.008
CD8+CD28+ T cells	14.59±2.70	13.72±4.92	13.44±3.86	0.708
CD8+CD28- T cells	12.32±3.10	13.64±8.52	18.11±8.92	0.033
Treg	2.40±0.59	3.22±0.89	3.83±1.24	0.001
CD19+ B cells	11.77±4.62	8.74±3.91	8.57±4.66	0.058
NK	16.24±6.33	20.22±11.92	20.98±8.91	0.350
NKT	6.85±4.20	5.54±4.63	6.37±4.22	0.590
γδT	5.62±4.66	5.17±7.08	5.11±4.42	0.963

Data were expressed as Mean±SD. Abbreviations: NSCLC: non-small cell lung cancer; NSCLC-D: NSCLC-at first diagnosis; NSCLC-R: NSCLC-at first relapse; SD: standard deviation; Treg: regulatory T cells.