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Bidirectional transport of CNO across MDCK monolayers and the impact of specific inhibitors on active efflux. Bidirectional transport of CNO (5 μM) across MDCK-Pgp/MDCK-MDR1 or BCRP-MDCK cell monolayers in the absence and presence of valspodar (1 μM) and Ko143 (0.5 μM). Open bars, A-B transport; closed bars, B-A transport. Data are presented as the mean ± SEM.
