Table 1. General characteristics of the included studies.
First Author | Year | Country | Study-center | Phase | Dose and schedule of decitabine | Trial Sponsor |
---|---|---|---|---|---|---|
Jacob et al. [10] | 2015 | India | NR | NR | 20 mg/m2 5-days 4 weeks | NR |
Yan et al. [11] | 2012 | America | Single-center | Phase II | 20 mg/m2 10-days 4 weeks | National Cancer Institute |
Ritchie et al. [12] | 2013 | America | Single-center | NR | 20 mg/m2 10-days 4 weeks | Leukemia Fighters™ |
Cashen et al. [13] | 2010 | America | Multicenter | Phase II | 20 mg/m2 5-days 4 weeks | NR |
Blum et al. [14] | 2010 | America | Single-center | Phase II | 20 mg/m2 10-days 4 weeks | National Cancer Institute |
Tawfik et al. [15] | 2014 | America | Single-center | NR | 20 mg/m2 5-days 4 weeks | National Cancer Institute |
Kantarjian et al. [16] | 2012 | America | Multicenter | Phase III | 20 mg/m2 5-days 4 weeks | MDACC and others |
Lübbert et al. [17] | 2011 | Germany | Multicenter | Phase II | 15 mg/m2 3-days 6weeks* | European LeukemiaNet |
Park et al. [18] | 2016 | Korea | Single-center | NR | 20 mg/m2 5-days 4 weeks | Yonsei University |
Abbreviations: NR: Not Reached; 15 mg/m2 3-days 6weeks*: 15 mg/m2, three times daily on 3 consecutive days. MDACC: M.D. Anderson Cancer Center.