Table 1. Quantification of Olaparib sensitivities (IC50) and RAD51 foci in EOC cell lines.
| IC50 Olaparib (µM) | RAD51 foci fold change | ||
|---|---|---|---|
| Resistant | OV1369 (R2) | 21.71 ± 10.33 | 4.5 ± 0.30 |
| TOV1369 | 9.02 ± 3.66 | 2.0 ± 0.05 | |
| OV866(2) | 8.11 ± 1.27 | 2.71 ± 0.21 | |
| OV90 | 7.04 ± 2.33 | 3.80 ± 0.23 | |
| Intermediate | TOV2223G | 2.99 ± 1.20 | 2.11 ± 0.08 |
| TOV3133D | 2.00 ± 1.15 | 1.53 ± 0.1 | |
| OV2295(R2) | 1.66 ± 0.99 | 2.01 ± 0.1 | |
| TOV3291G | 1.58 ± 0.23 | 1.64 ± 0.3 | |
| TOV2295(R) | 1.52 ± 1.14 | 2.23 ± 0.29 | |
| OV4485 | 0.90 ± 0.58 | 0.82 ± 0.2 | |
| OV3133(R) | 0.75 ± 0.04 | 1.05 ± 0.05 | |
| TOV3133G | 0.58 ± 0.44 | 1.37 ± 0.22 | |
| TOV2978G | 0.45 ± 0.30 | 1.85 ± 0.23 | |
| Sensitive | OV1946 | 0.07 ± 0.05 | 1.15 ± 0.11 |
| TOV3041G | 0.02 ± 0.01 | 2.05 ± 0.04 | |
| TOV1946 | 0.02 ± 0.007 | 1.35 ± 0.098 | |
| OV4453 | 0.01 ± 0.0009 | 1.03 ± 0.067 | |
| OV2295 | 0.0003 ± 0.0004 | 1.30 ± 0.2 |