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. 2017 Mar 29;8(25):40019–40036. doi: 10.18632/oncotarget.16685

Figure 14. Contribution of macroautophagy and chaperone-mediated autophagy in the malignant transformation and HCC growth in cirrhotic liver.

Figure 14

Macroautophagy serves as a tumor suppressor in hepatocytes in the cirrhotic liver. Macroautophagy loss promotes HCC. CMA compensate for the impaired macroutophagy for HCC survival in the cirrhotic liver.