Table 2. Association between two SNPs in 3′-UTR of SIRT2 gene and CRC risk in a Chinese population.
| SNP | Chr | Position | Genotype | Cases No. (%) | Controls No. (%) | OR (95% CI)a | Pa |
|---|---|---|---|---|---|---|---|
| rs2015 | 19 | 39369369 | CC | 252 (29.9) | 427 (24.9) | 1.00 (Reference) | |
| CA | 415 (49.3) | 884 (51.5) | 0.79 (0.65–0.96) | 0.019 | |||
| AA | 175 (20.8) | 407 (23.7) | 0.73 (0.58–0.92) | 0.009 | |||
| CA+AA | 590 (70.1) | 1,291 (75.1) | 0.77 (0.64–0.93) | 0.006 | |||
| rs2241703 | 19 | 39369514 | GG | 671 (79.7) | 1,335 (77.7) | 1.00 (Reference) | |
| GA | 162 (19.2) | 364 (21.2) | 0.89 (0.73–1.10) | 0.294 | |||
| AA | 9 (1.1) | 19 (1.1) | 1.02 (0.46–2.27) | 0.964 | |||
| GA+AA | 171 (20.3) | 383 (22.3) | 0.90 (0.73–1.10) | 0.308 |
aCalculated by logistic regression with adjustment for sex and age.