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. 2017 Apr 19;8(25):40705–40712. doi: 10.18632/oncotarget.17248

Figure 2. rSjP40 increased p27 promoter activity in LX-2 cells via transcription factors that bind to the -1740/-873 region of the p27 promoter.

Figure 2

(A) Diagram of the construction of p27 promoter truncated fragments. (B) Fluorescence activities of pGL3-basic, pGL3-p27, pGL3-p27a, pGL3-p27b, pGL3-p27c and pGL3-p27d in LX-2 cells were determined by dual-luciferase reporter assay. *P < 0.05, compared to pGL3-basic group. #P < 0.05, compared to pGL3-p27 group. (C) LX-2 cells were treated with or without rSjP40. Fluorescence activities of pGL3-p27, pGL3-p27a, pGL3-p27b, pGL3-p27c and pGL3-p27d were determined by dual-luciferase reporter assay. *P < 0.05, compared to each untreated group. NS, P > 0.05, no significant difference was found. The data are presented as the mean ± SEM of at least three independent experiments.