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. 2017 Apr 22;8(25):40140–40151. doi: 10.18632/oncotarget.17370

Table 1. Hematologic parameters from mice with various treatments for one week.

Hematology Unit Control 5-FU patch 5-FU IP inj.
(4.8mg, once)
5-FU IP inj.
(1.2mg, once/week)
Ave±SD Ave±SD Ave±SD Ave±SD
WBC 10e3/uL 7.12±2.01 5.18±0.58b 1.95±0.75b 4.68±0.31b
RBC 10e6/uL 10.00±0.28 8.86±0.14 4.49±0.64b 8.09±0.66
HGB g/dL 14.90±0.36 13.87±0.23 6.53±0.90b 12.57±1.08
HCT % 48.83±1.25 47.30±1.08 22.73±3.09b 43.57±2.65
PLT 10e3/uL 1259±58 1179.±454 1019±187 950±780
Neut 10e3/uL 0.53±0.22 0.62±0.16 0.04±0.01b 0.29±0.08b
Lymph 10e3/uL 6.27±1.75 4.28±0.33 1.88±0.73b 4.19±0.41
Mono 10e3/uL 0.07±0.02 0.07±0.03 0.00±0.00 0.04±0.01
Luc 10e3/uL 0.08±0.05 0.02±0.01 0.01±0.01b 0.04±0.03
%Retic % 3.56±0.09 9.49±1.40a 0.34±0.19b 18.38±14.37a
#Retic 10e9/L 356.23±14.87 839±112a 14.50±6.00b 1446±1061a

Data presented as mean±SD, n = 4. a and b represent significant increase and decrease at p < 0.05 compared to control values, respectively.