Table 1. Hematologic parameters from mice with various treatments for one week.
Hematology | Unit | Control | 5-FU patch | 5-FU IP inj. (4.8mg, once) |
5-FU IP inj. (1.2mg, once/week) |
---|---|---|---|---|---|
Ave±SD | Ave±SD | Ave±SD | Ave±SD | ||
WBC | 10e3/uL | 7.12±2.01 | 5.18±0.58b | 1.95±0.75b | 4.68±0.31b |
RBC | 10e6/uL | 10.00±0.28 | 8.86±0.14 | 4.49±0.64b | 8.09±0.66 |
HGB | g/dL | 14.90±0.36 | 13.87±0.23 | 6.53±0.90b | 12.57±1.08 |
HCT | % | 48.83±1.25 | 47.30±1.08 | 22.73±3.09b | 43.57±2.65 |
PLT | 10e3/uL | 1259±58 | 1179.±454 | 1019±187 | 950±780 |
Neut | 10e3/uL | 0.53±0.22 | 0.62±0.16 | 0.04±0.01b | 0.29±0.08b |
Lymph | 10e3/uL | 6.27±1.75 | 4.28±0.33 | 1.88±0.73b | 4.19±0.41 |
Mono | 10e3/uL | 0.07±0.02 | 0.07±0.03 | 0.00±0.00 | 0.04±0.01 |
Luc | 10e3/uL | 0.08±0.05 | 0.02±0.01 | 0.01±0.01b | 0.04±0.03 |
%Retic | % | 3.56±0.09 | 9.49±1.40a | 0.34±0.19b | 18.38±14.37a |
#Retic | 10e9/L | 356.23±14.87 | 839±112a | 14.50±6.00b | 1446±1061a |
Data presented as mean±SD, n = 4. a and b represent significant increase and decrease at p < 0.05 compared to control values, respectively.