Table 1. Clinical baseline and coronary angiography characters.
| Variable | Combined therapy (n =114 ) |
Double-dose (n = 116) |
P value |
|---|---|---|---|
| Male, n (%) | 60 (52.6) | 59 (50.9) | 0.79 |
| Age, years | 84.2±2.9 | 84.0±1.8 | 0.73 |
| BMI, kg/m2 | 25.6±3.5 | 25.4±3.9 | 0.72 |
| STEMI, n (%) | 46(40.4) | 43(37.1) | 0.61 |
| HT, n (%) | 81 (71.1) | 80 (69.0) | 0.73 |
| DM, n (%) | 46(40.4) | 42(36.2) | 0.52 |
| Current smokers, n (%) | 13 (11.4) | 16 (13.8) | 0.59 |
| Previous MI, n (%) | 22 (19.3) | 17 (14.7) | 0.35 |
| Previous PCI, n (%) | 16 (14.0) | 12 (10.3) | 0.39 |
| Previous stroke, n (%) | 14 (12.3) | 16 (13.8) | 0.73 |
| LVEF, (%) | 61.7±11.4 | 61.2±9.9 | 0.79 |
| Aspirin, n (%) | 98(86.0) | 92(79.3) | 0.18 |
| clopidogrel, n (%) | 85 (74.6) | 78 (67.2) | 0.22 |
| ACEI/ARB, n (%) | 89 (78.1) | 85(73.3) | 0.40 |
| β-blocker, n (%) | 76 (66.7) | 74 (63.8) | 0.65 |
| Alt, IU/L | 22.7±15.5 | 22.1±17.6 | 0.88 |
| CRE, umol/L | 85.3±22.3 | 79.6±25.2 | 0.44 |
| hsCRP, mg/L | 3.1±1.6 | 3.2±1.8 | 0.42 |
| LDL-C, mmol/L | 2.2±0.6 | 2.3±0.8 | 0.15 |
| HDL-C, mmol/L | 1.2±0.3 | 1.3±0.3 | 0.12 |
| TG, mmol/L | 1.5±1.0 | 1.6±1.5 | 0.32 |
| Left main intervention, n (%) | 15 (13.2) | 15 (12.9) | 0.33 |
| Single-vessel disease, n (%) | 40 (35.1) | 48 (41.4) | 0.33 |
| No. of vessel diseases, n | 2.1±1.1 | 1.9±0.9 | 0.87 |
| contrast media, ml | 105.8±66.9 | 103.2±67.6 | 0.61 |
| PCI patients, n (%) | 52 (45.6) | 50 (43.1) | 0.70 |
| In PCI patients | |||
| Stent number (n) | 1.7±0.7 | 1.9±1.0 | 0.14 |
| Stent diameter, mm | 3.0±0.5 | 3.0±0.4 | 0.72 |
| Total stent length, mm | 43.8±20.7 | 48.8±28.3 | 0.16 |
Age, gender, hypertension, lipid level, liver function, renal function, medical therapy and angiography characteristics were similar between the two groups.
Abbreviations: BMI, body mass index; STEMI, ST-segment elevation myocardial infarction; LVEF, left ventricular ejection fraction; ACEI, Angiotensin-converting enzyme inhibitors; ARB, angiotensin receptor blocker; ALT, alanine aminotransferase; CRE, creatinine; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; CK, creatine kinase; hsCRP, high sensitive C-reactive protein; PCI, percutaneous coronary intervention.