Figure 3. Cumulative meta-analysis of published and unpublished data of the association between the BIM deletion polymorphism and progression-free survival in EGFR-TKI-treated NSCLC patients.

Estimates were adjusted for age, sex, smoking history, stage, ECOG status, histology, EGFR mutation and line of treatment. Zhong J et al. was omitted from this figure as both summary statistics and individual patient data (IPD) were not available. * indicates IPD was unavailable, † indicates summary HRs were calculated by the authors of this paper according to the methods described in the Methods section.