Figure 3. Selective reduction of urinary RKIP in ccRCC.
(A) Urinary expression of ~23,322 m/z mass peak (RKIP) in ccRCC vs. PCa and HS samples as measured by SELDI analysis. (B) Overall intensity (μA) of RKIP (23,320 m/z) in all samples as represented by the box-plots. (C) urinary levels of RKIP in ccRCC Vs. PCa and HS as measured by western blotting. Each sample used in WB analysis was a pool of 4 samples. HS= Healthy Subjects; PCa= Prostate cancer; ccRCC= clear cells Renal Cell Carcinoma; PC: positive control (protein extract from Rat hyppocampus); #: HS vs RCC p-value < 0.001; §:PCa vs ccRCC p-value < 0.01 (Mann Whitney-U test).
