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. 2017 Mar 31;8(25):41740–41748. doi: 10.18632/oncotarget.16771

Table 2. Meta-analysis of short and long-term outcomes.

Outcome of interest Studies Participants OR/WMD 95% CI P-value I2 (%)
Clinicopathologic features
Male gender 3 1231 0.58 0.46, 0.75 <0.001 0
Age 4 1470 0.10 -1.28, 1.47 0.10 40
Body mass index 2 695 -0.26 -1.26, 0.74 0.62 0
Preoperative anemiaa 2 775 2.51 1.83, 3.45 <0.001 0
ASA > 2 2 748 1.15 0.59, 2.24 0.69 76
Extended or major resection 4 1470 1.64 1.28, 2.09 <0.001 0
Duration of surgery (min) 2 775 55.64 42.14, 69.14 <0.001 0
Blood loss (mL) 4 1470 726.88 376,91, 1076.84 <0.001 93
Tumor size (cm) 2 695 0.95 -0.13, 2.03 0.09 78
Tumor number 2 695 -0.03 -0.49, 0.44 0.90 59
Negative surgical margin 4 1470 1.03 0.70, 1.51 0.89 0
Postoperative outcomes
Overall morbidity 6 2833 1.98 1.49, 2.33 <0.001 51
Major complication 4 2226 2.12 1.26, 3.58 0.005 76
Mortality 5 2821 4.13 1.96, 8.72 <0.001 51
Length of stay (day) 3 2099 4.42 1.15, 7.69 0.008 82
Long-term outcomes
Overall survival 21 8732 1.24 1.11, 1.38 0.0002 71
Disease-free survival 11 5018 1.38 1.23, 1.56 <0.001 17

Abbreviations: OR=odds ratio, WMD=weighted mean difference, CI= confidence interval,

ASA= American Society of Anesthesiologists