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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: J Trauma Acute Care Surg. 2017 Aug;83(2):263–270. doi: 10.1097/TA.0000000000001513

Figure 1.

Figure 1

Mean arterial blood pressure (MABP) of Control, Hemorrhagic Shock (HS), Hemorrhagic Shock + Enteral Tranexamic Acid (HS + TXA), and Hemorrhagic Shock + Vehicle (HS + Vehicle) groups. MABP was decreased to a mean of 35 mmHg over several minutes by the serial withdrawal of small aliquots of blood (0.5 ml/min). Reperfusion was carried out in analogous fashion by slow reinfusion of shed blood (0.5 ml/min). **p < 0.01 Control vs. HS + TXA and #p < 0.0001 HS, HS + Vehicle vs. HS + TXA and Control; #p < 0.0001 Control vs. HS, HS + Vehicle, HS + TXA during ischemia period as per experimental design. There were no statistical differences between HS and HS + Vehicle groups at any time points. Results shown as Mean ± SD.