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Comparison of GRCh37 and GRCh38 genome accessibility masks
| N | L | H | Z | Q | P | |
|---|---|---|---|---|---|---|
| GRCh37-strict | 7.66% | 1.13% | 0.55% | 17.20% | 2.98% | 70.49% |
| GRCh37-pilot | 7.66% | 1.13% | 0.24% | 2.74% | 88.23% | |
| GRCh38-strict | 5.33% | 1.44% | 1.04% | 18.07% | 0.03% | 74.09% |
| GRCh38-pilot | 5.33% | 1.44% | 0.56% | 3.67% | 89.00% |
H: accumulative read depth too high; L: accumulative read depth too low; N: bases that are “N”; P: sites passed the accessibility test; Q: mapping quality less than cutoff; Z: too many reads with mapping quality 0.
