Table 1.
Composition of immune cell subsets in peripheral blood, intervillous blood, and decidua parietalis.
| Subpopulation | n | Peripheral blood (PB) | Intervillous blood (IVB) | Decidua parietalis (DP) | Friedman test, p | Wilcoxon test, p × 3 | ||
|---|---|---|---|---|---|---|---|---|
| PB vs IVB | PB vs DP | IVB vs DP | ||||||
| T cells (CD45+/CD3+) | 10 | 63.7 (54.3–71.5) | 58.5 (30.2–70–4) | 61.7 (51.1–77.7) | 0.601 | |||
| CD4+ T cells (CD3+/CD4+) | 11 | 65.4 (40.0–82.6) | 52.8 (26.0–73.5) | 46.9 (38.1–59.5) | 0.087 | |||
| CD8+ T cells (CD3+/CD8+) | 11 | 27.2 (14.3–54.8) | 35.3 (19.4–55.9) | 45.4 (30.7–57.0) | 0.117 | |||
| Double negative T cells (CD3+/CD4−CD8−) | 11 | 5.0 (1.4–14.0) | 10.9 (3.5–17.5) | 5.1 (2.5–23.4) | 0.002 | 0.162 | 0.99 | 0.162 |
| B cells (CD45+/CD19+CD20+) | 9 | 5.1 (3.6–11.6) | 12.4 (3.8–28.7) | 1.2 (0.4–5.4) | <0.0001 | 0.023 | 0.012 | 0.012 |
| Monocytes/macrophages (CD45+/CD14+) | 9 | 23.2 (13.2–26.8) | 15.9 (5.8–45.7) | 6.3 (4.0–14.5) | 0.031 | 0.99 | 0.012 | 0.294 |
| Classical NK cells (CD45+/CD56dim CD3−) | 10 | 3.7 (1.4–6.1) | 4.6 (2.2–18.3) | 2.8 (2.0–3.7) | 0.0047 | 0.012 | 0.902 | 0.012 |
| Non-classical NK cells (CD45+/CD56high CD3−) | 10 | 0.5 (0.3–2–0) | 1.1 (0.4–2.3) | 18.8 (8.6–30.4) | <0.0001 | 0.006 | 0.006 | 0.006 |
| NKT-like cells (CD45+/CD56+ CD3+) | 10 | 2.2 (0.8–5.4) | 3.9 (0.9–9–7) | 5.9 (2.8–8.6) | 0.0020 | 0.029 | 0.006 | 0.194 |
Subpopulation name, extracellular markers used for identification by flow cytometry and number of paired samples (n). Median values with range of observed values in parenthesis.